If you are interested in the study, you can choose to participate in one of the three cohorts. The differences are the following:
Important: if you have a BMI (Body Mass Index) below 18.5 or a lean musculature (for example, if you are an elite athlete), these are not exclusion criteria, but we do not recommend you participate. The filament of the glucose sensor could reach your muscle, which is not dangerous, but on the one hand is painful and on the other hand, distorts the data. If necessary, calculate your BMI here.
Select the cohort you're interested in and check all boxes that apply to you to find out if you're eligible.
Note, cohort V is not yet open, if you register for this cohort, you will have to wait several months before participating.
The project is entirely coordinated digitally via the website. This means that no face-to-face interviews or medical appointments will be organized. All instructions will be conveyed by the website, emails and text messages.
The project is carried out in compliance with the requirements of Swiss legislation. We also comply with the internationally approved guidelines. The Geneva ethics commission has reviewed and authorized the project. A description of the study can also be found on the website of the Federal Office of Public Health (number SNCTP000002833) and the platform ClinicalTrial.gov.
All necessary information will be provided on this website at the appropriate time.
||Approx. 5 mins|
|Test MyFoodRepo app.||
|Preparation for the tracking weeks||
||Approx. 1h 30 min.|
|Stool sample collection||
||Approx. 15 min.|
Only mandatory for the participants of the B and C Cohorts.
|Additional tracking weeks||
Only for the participants of the C cohort
|14 days and 2 months|
|End of data collection||
||Approx. 15 min.|
||Within 6 months of completing study|
Only mandatory for the participants of the B and C Cohorts.
|2 & 3||110 g white bread||110 g white gluten-free bread|
|4 & 5||110 g white bread, 30 g butter||55 g white bread, 50 g dark chocolate||110 g gluten-free white bread, 30 g butter||55 g gluten-free white bread, 50 g dark chocolate|
|6 & 7||glucose drink (50g)|
You will not be allowed to add anything to these meals (for example, no jam on the bread), and will not be allowed to eat anything else for two hours after these six breakfasts. For the others meals during the two weeks, follow your daily routine and dietary habits.
Cohort C participants will have to eat these six breakfasts twice.
You should participate in this study only at your own will. If you choose not to participate or if you choose to participate and reconsider your decision during the course of the study, you will not have to justify your withdrawal. You can ask your questions using the contact form.
As a participant in the study, you will be expected to follow the instructions that will be given to you and comply with the study plan.
The study does not pose any major risk. The data will be collected using non-invasive methods, except for the FreeStyle Libre sensor used to measure the glucose level (with an applicator, you will have to insert a very thin filament beneath your skin surface). The procedure meets all safety requirements. The glucose sensor can provoke a skin allergic reaction. In these cases, you will have to remove it, contact the sensor provider and interrupt the study.
If you discover that you are pregnant during the study, you should inform the investigator immediately. You will then have to interrupt the study.
As there are no visits to the physician scheduled during the study, we cannot commit to providing diagnoses related to your health. However, depending on your individual needs, you will be able to contact a doctor associated with the research team of this project.
Project data is handled with the utmost discretion and will be only accessible to authorized staff who need the data to complete their duties within the scope of the research project. Generation, transmission, storage and analysis of health-related data and the storage of biological samples within this project strictly follow the current Swiss legal requirements for data protection and are performed according to the Swiss Ordinance on Clinical Trials in Human Research (ClinO), Art 5.
Coding will safeguard participants' confidentiality. This means that your sensitive data will not be directly linked to your identifiable data (name, email, address, date of birth, etc), but they will be associated to identification code numbers (de-identification). Only the main investigator will have access to the coding key to link your sensitive data to your identifiable participant data. In case of a publication in a scientific journal, the aggregated data will not be attributable to you as a person. Your name will never appear in an open or public document. Occasionally, scientific journals require the raw data. In this case, the individual data transmitted will always be coded and therefore it will not be possible to identify you as a person.
You will have the choice to sign a separate consent form specifically for the reuse of your data. If you accept, your data and biological samples may subsequently be used in other research projects or sent for analysis to another biobank, in Switzerland or abroad (re-use) for use in other research projects. This biobank would have to comply with the same standards and requirements as the biobank of this project.
The project may be inspected by the ethics committee responsible for the initial control and authorization of the project. In this case, the project investigator may need to communicate your data for the inspections.
You can withdraw from the study at any time if you wish. Health-related data and biological material collected up to that time will be anonymized and still be analyzed so as not to compromise the value of the study as a whole. In addition, you should withdraw from the study for the following reasons:
In case of withdrawal, the biological material, i.e. the DNA extracted from the stool sample, will be permanently destroyed and your health-related data anonymized. It will, therefore, be impossible to trace the origin of the data and samples.
If you are participating in this project, you will not be paid. The participants’ benefits are given in the above section.
EPFL is responsible for any damage you may suffer in relation to research activities. The conditions and procedure are laid down by law. Any injury or damage due to the participation in the above-mentioned research project and for which the responsibility of the EPFL can be established is covered by the general liability insurance of EPFL (insurance policy no. 501 402430.002 of La Mobilière Assurances), in accordance with the terms and conditions of the insurance. In any case, it is your responsibility to have sufficient coverage in case of illness and accident. In case of doubt, you can contact us.
The project is financed mainly by the Kristian Gerhard Jebsen foundation. This foundation aims to enhance the well-being of people and promote human and social development, through support of grantees in the areas of health, education, science, culture and environment, in Switzerland and abroad. No food-related or pharmaceutical-related industry is financing this study.
In case of doubt, concerns or emergency during or after the project, you can contact us at any time.
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After signing up, you will be redirected to the declaration of consent, you will have to read it and decide if you want to refuse or accept it.
If none of the buttons below are enabled (the active buttons are green), return to the 'Participants able to participate' section, select the criteria that apply to you and click on the 'Check eligibility' button. Buttons will be enabled if you satisfy eligibility criteria.